Genistein 446-72-0

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Product Details

Product name

Genistein

Specification

98%  

Package

25kg/drum

Genistein is a variety of isoflavone which is most active, the product Genistein of our company is derived from dry and mature fruit of bean plant sophora Japonica. It is a pure and single element. It is a compound of heterocycle polyphenol.
Genistein can combine with estrogen receptor and have weak estrogen effect. So it is also called phytoestrogen. It is antagonistic to estrogen. It has protective effect or hormone related diseases. It can improve and prevent climacteric syndrome and osteoporosis. It can serve as food supplement to be widely used in various healthy food for the middle-aged and old people.
Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities
Function
1. Genistein,natural genistein supplier has the function of anti-oxidation;
2. Genistein,natural genistein supplier has the properties of estrogen and anti-estrogen;
3. Genistein,natural genistein supplier can suppress the activation of topoisomerase II, and suppress the activation of
protein tyrosine kinase(PTK);
4. Genistein,natural genistein supplier brings out cell's procedure death, improves the anticancer drug's effect and suppresses the blood vessel to be produced etc.
Applications
1.Applied in the field of pharmaceutical, it can be made into suppositories, lotions, tablets,capsules and so on;
2. Applied in the field of health care products, it can be used as beauty care products for women and also it can prevent blood diseases and cancer.

Items

Specification

Method

Results

Color

light-yellow

Organoleptic

Conform

Odour

Characteristic

Organoleptic

Conform

Appearance

Fine Powder

Organoleptic

Conform

Analytical Quality

Identification

Identical to R.S. sample

HPLC

Identical

Genistein

≥98 %

HPLC(on anhydrous basis)

98.67%

Sieve analysis

90% through 80 mesh

USP32<786>

Conform

Water(KF)

≤1.0 %

Eur.Ph.6.0 [2.5.12]

0.45%

Total Ash

≤1.0 %

Eur.Ph.6.0 [2.4.16]

0.03%

Bulk density

30~50 g/100ml

Eur.Ph.6.0 [2.9.15]

31g/100ml

Tap density

50~70g/100ml

Eur.Ph.6.0 [2.9.15]

50g/100ml

Contaminants

Lead(Pb)

≤3.0 mg/kg

Eur.Ph.6.0 [2.2.58] ICP-MS

0.0840mg/kg

Arsenic(As)

≤2.0 mg/kg

Eur.Ph.6.0 [2.2.58] ICP-MS

0.0324mg/kg

Cadmium(Cd)

≤1.0 mg/kg

Eur.Ph.6.0 [2.2.58] ICP-MS

<0.01 mg/kg

Mercury( Hg)

≤0.1 mg/kg

Eur.Ph.6.0 [2.2.58] ICP-MS

0.0114 mg/kg

Solvents Residue

Meet Eur. Ph 5.0<5.4>

Eur.Ph.6.0 [2.4.28]

Conform

Pesticides Residue

Meet USP Requirements

USP32<561>

Conform

Contact Us
Shanghai Shine High International Trade Co.,Ltd
Add:Room 308,North Wanke Creative quarter,No2000,Dongming Road, Pudong new district,Shanghai, China
Tel:86-21-66531378
Fax:86-21-66531373
Email:sales@ingredient4health.com
Web:http://www.ingredient4health.com/

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